Testing to possess AZF microdeletions is carried out in the brand new ninety NOA men which have typical karyotype. With the EAA/EMQN conditions, AZF part microdeletions on Y-chromosome have been found in patients with a volume out-of 2.22%. The brand new were not successful amplification regarding sY254 and you can sY255 markers indicates an entire removal from the AZF sandwich-area (Figure twelve).

Discussion

Chromosomal abnormalities have emerged as one of the significant hereditary things contributing to male sterility. Within data, the new incidence out-of big chromosomal defects is actually % for the NOA with primary sterility. This is less than during the early in the day degree out-of Tunisian populace in order to %, but the incidence various other populations has been discovered become ranging from 5.43% and % (Dining table dos).