Multiple population-dependent studies and you will observational studies have shown you to definitely oophorectomy are associated that have a greater likelihood of colorectal cancers (CRC), and you may hormones replacement for treatment could have been regarding the a reduction in the possibility of colorectal malignant tumors. This study is actually carried out to research if or not hysterectomy, that could affect the levels of feminine hormonal, was of the a threat of cancer of your particular gastrointestinal tract.
Procedures
That it population-based retrospective cohort analysis was conducted using insurance coverage study available with the Insurance Comment and Investigations Solution (HIRA) out of . The brand new hysterectomy classification included forty- in order to 59-year-dated ladies who underwent hysterectomy having uterine leiomyoma or uterine endometriosis out of . The control classification incorporated feminine old forty to 59 years which decided to go to medical institutions getting medical examination out-of .
Efficiency
New hysterectomy and you can low-hysterectomhy groups manufactured 66,204 and you will 89,768 sufferers, respectively. The latest median age regarding the non-hysterectomy group and you may hysterectomy group have been 48 (range: 43–53) and you may 46 (range: 44–49) many years, correspondingly.